BETAThis platform is under active development; bugs, missing features, and risk of data loss are present. Thank you for your support!

Reproduction and genetic variation

Learn it by playing

Answer these questions to earn energy, then fish and explore. No account needed.

For teachers: ready-to-use lesson slides, revision notes, diagrams for Reproduction and genetic variation (NGSS Middle School Science, Biology) — use them in your lesson, or run the topic as an interactive class activity your students play as a live game.

Lesson notes

Introduction to Reproduction and Genetic Variation

  • **Genetic variation** refers to differences in DNA among individuals of the same species.
  • Variation can be observed as **phenotypic variation** in traits like height or flower color.
  • Two main types of reproduction: **asexual** (identical offspring) and **sexual** (variation).
  • Sexual reproduction combines DNA from two parents, creating unique offspring.

Asexual Reproduction

  • Offspring are **genetically identical** to the parent (clones).
  • Occurs in bacteria (binary fission), yeast (budding), and some plants (runners).
  • No fusion of gametes; no genetic variation except by mutation.
  • Advantage: rapid population growth in stable environments.

Sexual Reproduction and Variation

  • Involves **meiosis** to produce gametes (sperm and egg) with half the DNA.
  • **Crossing over** during meiosis swaps DNA between homologous chromosomes, creating new allele combinations.
  • **Independent assortment** of chromosomes during meiosis shuffles genes.
  • **Random fertilization** combines any sperm with any egg, increasing variation.

Sources of Genetic Variation

  • **Mutations** are changes in DNA sequence; they are the ultimate source of new alleles.
  • Mutations can be **neutral**, **harmful**, or **beneficial**; most are neutral.
  • **Genetic recombination** (crossing over and independent assortment) creates new combinations of existing alleles.
  • **Gene flow** (movement of alleles between populations) introduces variation.

Types of Mutations

  • **Small-scale** mutations: base-pair substitutions (point mutations) and indels (insertions/deletions).
  • **Large-scale** mutations: chromosomal rearrangements (translocations, inversions) and copy number changes.
  • **Polyploidy** (extra sets of chromosomes) is a type of chromosomal mutation common in plants.
  • Mutations can occur in **somatic cells** (not inherited) or **germline cells** (passed to offspring).

Genetic Variation in Populations

  • **Polymorphic genes** have more than one allele in a population.
  • Variation is measured as the percentage of polymorphic loci or heterozygosity.
  • **Natural selection**, **genetic drift**, and **gene flow** affect variation levels.
  • **Balanced polymorphisms** (e.g., heterozygote advantage) maintain variation.

RNA Viruses and Variation

  • RNA viruses have high mutation rates due to lack of proofreading.
  • **Genetic recombination** in RNA viruses (e.g., influenza, HIV) generates new variants.
  • Recombination can lead to outbreaks when new viral strains emerge.

Monohybrid cross showing 3:1 phenotype ratio from heterozygous parents.

Genetic cross: Bb × Bbflower color (B=purple dominant, b=white)Parent 1 gametesParent 2 gametesBbBbBBBbBbbbGenotype ratio 1 BB : 2 Bb : 1 bbPhenotype ratio 3 dominant : 1 recessive

DNA double helix with complementary base pairing (A-T, C-G).

DNA — double helixSugar–phosphate backboneBase pairHydrogen bondsA – TC – G

Meiosis reduces chromosome number and generates variation through crossing over and independent assortment.

Meiosis OverviewParent cell (2n)Meiosis I: homologous pairs separateMeiosis II: sister chromatids separateFour haploid gametes (n)Art: bioicons.com

Slides

Sign up free to view the lesson slides

Step through every slide for this topic — plus flashcards and revision notes — with a free account.

Practice questions

Free preview — 8 of 40 questions. Sign up to see them all.
  1. 1.What is the main difference between asexual and sexual reproduction?

    Easy
    • AAsexual reproduction produces genetically identical offspring; sexual reproduction produces genetically varied offspring.
    • BAsexual reproduction produces genetically varied offspring; sexual reproduction produces genetically identical offspring.
    • CBoth produce genetically identical offspring.
    • DBoth produce genetically varied offspring.
  2. 2.Which process is the ultimate source of genetic variation?

    Easy
    • AMutation
    • BNatural selection
    • CGenetic drift
    • DGene flow
  3. 3.In a monohybrid cross between two heterozygous parents (Bb x Bb), what is the expected phenotypic ratio of dominant to recessive traits?

    Medium
    Genetic cross: Bb × Bbseed shape (B=round dominant, b=wrinkled)Parent 1 gametesParent 2 gametesBbBbBBBbBbbbGenotype ratio 1 BB : 2 Bb : 1 bbPhenotype ratio 3 dominant : 1 recessive
    • A3:1
    • B1:2:1
    • C1:1
    • D9:3:3:1
  4. 4.During which stage of meiosis does crossing over occur, leading to genetic recombination?

    Medium
    • AProphase I
    • BMetaphase I
    • CAnaphase II
    • DTelophase II
  5. 5.A population of insects has two alleles for wing color: green (G) and brown (g). The frequency of the green allele is 0.7. Assuming Hardy-Weinberg equilibrium, what is the expected frequency of heterozygous individuals?

    Hard
    • A0.42
    • B0.49
    • C0.09
    • D0.21
  6. 6.Which of the following is an example of a large-scale structural variation in the genome?

    Hard
    • AA base-pair substitution
    • BA deletion of a 10 kb segment
    • CA single nucleotide polymorphism
    • DAn insertion of one base
  7. 7.A farmer uses cuttings from a single potato plant to grow many new plants. This is an example of which type of reproduction?

    Easy
    • AAsexual reproduction
    • BSexual reproduction
    • CFertilization
    • DMeiosis
  8. 8.Which diagram correctly shows the structure of DNA?

    Medium
    DNA — double helixSugar–phosphate backboneBase pairHydrogen bondsA – TC – G
    • AA double helix with sugar-phosphate backbones and complementary base pairs
    • BA single strand of nucleotides
    • CA circular molecule with no base pairing
    • DA triple helix with three backbones

Unlock all 40 questions, flashcards & more

Create a free account to see every question, the slides, flashcards and revision notes for this topic.

Past papers

Past-paper practice for this topic is coming soon.
Coming soon