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Excretion In Humans

边玩边学

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课程笔记

Excretion: Definition & Organs

  • Excretion is the removal of waste products of metabolic reactions, toxic materials, and substances in excess of requirements.
  • The main excretory organs are the lungs (excrete CO₂), kidneys (excrete excess water, salts, and urea), and the liver (produces urea via deamination).
  • Egestion (removal of undigested food via the anus) is not excretion.
  • CO₂ must be excreted because it dissolves in water to form an acidic solution, lowering pH and reducing enzyme activity.
  • Urea is toxic at high concentrations and must be removed.

The Urinary System

  • Kidneys: two bean-shaped organs that filter blood to form urine.
  • Ureter: tube connecting each kidney to the bladder.
  • Bladder: stores urine until it is released.
  • Urethra: tube that carries urine from the bladder to the exterior.
  • Note: ureter and urethra are different tubes — do not confuse them.

The excretory system in humans

The excretory system in humans

Kidney Function & the Nephron

  • Kidneys regulate water content of blood (maintains blood pressure) and excrete urea and excess salts.
  • Each kidney contains about 1 million nephrons (kidney tubules).
  • Nephrons start in the cortex, loop into the medulla, and return to the cortex; urine drains into the renal pelvis then ureter.

The structure of a human kidney

The structure of a human kidney

Ultrafiltration

  • Blood enters the glomerulus via an afferent arteriole at high pressure.
  • Capillaries narrow, increasing pressure, forcing small molecules out into Bowman's capsule — this is ultrafiltration.
  • Filtrate contains: glucose, water, urea, salts. Large molecules like proteins remain in blood.
  • The filtrate then flows through the nephron for selective reabsorption.

Diagram showing the process of ultrafiltration

Diagram showing the process of ultrafiltration

Selective Reabsorption

  • Glucose is reabsorbed by active transport in the proximal convoluted tubule (PCT).
  • PCT cells have many mitochondria to supply energy for active transport.
  • In a healthy person, all glucose is reabsorbed; in diabetes, excess glucose remains in urine.
  • Salts are reabsorbed in the Loop of Henle by diffusion and active transport; water follows by osmosis.
  • Water reabsorption in the collecting duct varies according to the body's needs.

Diagram showing the reabsorption of glucose

Diagram showing the reabsorption of glucose

Role of the Liver: Deamination

  • Excess amino acids cannot be stored and are broken down in the liver by deamination.
  • The amino group (-NH₂) is removed; the carbon part is converted to glycogen and stored.
  • The nitrogen part is converted to ammonia (highly toxic), then immediately to urea (less toxic).
  • Urea dissolves in blood, is carried to the kidneys, and excreted in urine (a small amount in sweat).
  • High urea levels can cause cell death, reduced insulin response, and deposits in blood vessels.

Amino acid groups

Amino acid groups

Excretory Products Summary

  • Lungs: excrete CO₂ (from aerobic respiration).
  • Kidneys: excrete excess water, salts, and urea.
  • Liver: produces urea from deamination of excess amino acids; also breaks down alcohol and toxins.
  • Skin: excretes small amounts of urea and salts in sweat.

Waste substances

Waste substances

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练习题

免费预览——57 题中的 8 题。注册即可查看全部。
  1. 1.What is urea produced from?

    Easy
    • AAmino acids
    • BFatty acids
    • CGlucose
    • DGlycerol
  2. 2.Which of the following is a correct example of excretion in mammals?

    Easy
    • AThe removal of excess salts from the blood.
    • BThe production of carbon dioxide from aerobic respiration.
    • CThe removal of undigested food via the anus.
    • DThe release of hormones from glands.
  3. 3.Which of the following is not a main function of the kidneys in a healthy person?

    Medium
    • ATo breakdown toxins.
    • BTo reabsorb all glucose.
    • CTo regulate blood pressure.
    • DTo eliminate excess sodium and potassium ions.
  4. 4.Which of the following substances would be reabsorbed by the kidneys?

    Medium
    • ASalts and glucose
    • BSalts, urea and glycogen
    • CSalts and glycogen
    • DUrea and glucose
  5. 5.Which statement about urea is correct?

    Easy
    • AUrea is formed from excess amino acids in the liver and excreted by the kidneys.
    • BUrea is formed from excess amino acids in the kidneys and excreted by the liver.
    • CUrea is formed from excess glucose in the liver and egested by the kidneys.
    • DUrea is formed from excess glucose in the kidneys and egested by the liver.
  6. 6.The table shows the composition of blood entering the kidneys. | Substance | Blood (%) | |---|---| | Glucose | 0.20 | | Urea | 0.01 | | Protein | 7.00 | Which row shows the composition of urine in a healthy person?

    Medium
    • Aglucose 0.00%, urea 2.50%, protein 0.00%
    • Bglucose 0.00%, urea 2.50%, protein 3.50%
    • Cglucose 2.00%, urea 0.00%, protein 7.00%
    • Dglucose 0.20%, urea 0.01%, protein 0.00%
  7. 7.A person produced 1.75 dm³ of urine on a cool day. How will the volume and concentration of urine change on a hot day, if fluid intake is the same?

    Medium
    • Avolume decreases, concentration increases
    • Bvolume increases, concentration decreases
    • Cvolume decreases, concentration decreases
    • Dvolume increases, concentration increases
  8. 8.Which of the following organs are responsible for removing excretory products from the blood?

    Easy
    • AKidneys and lungs
    • BBladder and kidneys
    • CLungs and liver
    • DBladder and liver

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